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On a GLP-1? The muscle you must not lose
Semaglutide and tirzepatide strip weight fast — but a large share of it can be muscle, not just fat. Here is the protein-and-training protocol that protects lean mass, and how Misi tracks it.
Creatine is not just for muscle — the brain, ageing and the women’s case
Creatine is the most-researched supplement in sport — and the evidence now reaches well beyond the gym, into cognition, healthy ageing and women’s health. Here is what holds up, and one lab quirk Misi accounts for.
Menopause, muscle and bone — defending both with protein and lifting
The menopause transition accelerates the loss of muscle and bone — but the two most effective countermeasures are firmly within your control. Here is the protein-and-training case, and how Misi tracks it.
How much protein actually builds muscle — and why leucine pulls the trigger
Building muscle comes down to two numbers most people never track: how much total protein you eat per kilogram of bodyweight, and how much leucine lands in each meal. Misi plots both against the evidence.
Protein quality, not just quantity — why leucine decides if a meal counts
Two meals can have the same protein on the label and do completely different things to your muscle. The difference is amino-acid quality — and above all, leucine. Here is how to tell, and how Misi tracks it.
The daily macro problem — hitting your numbers without a spreadsheet
Real food does not arrive in round numbers. Most days you finish 20g of protein short or a little over on carbs — and fixing it by hand is fiddly. Misi turns it into a single dial.
Your muscles are an endocrine organ: what “myokines” actually do
Muscle isn’t just for movement. When it contracts, it releases signalling molecules called myokines that talk to your fat, liver, and brain — which is why building and using muscle changes your whole-body metabolism, not just your strength.
Muscle is where most of your blood sugar goes
After a meal, the majority of the glucose you absorb is taken up by skeletal muscle. That makes trained, insulin-sensitive muscle one of the body’s most important defences against high blood sugar and type 2 diabetes.
Muscle is your body’s reserve for illness and aging
Beyond movement and metabolism, skeletal muscle is the body’s main store of amino acids — a reserve it draws on during illness, injury, and recovery. That reserve is a big reason muscle mass predicts how well people withstand serious health challenges.