PhenoAge explained — what your bloods say about your real age
PhenoAge turns nine standard blood markers into a single number: how old your body is actually functioning. Here is how it works and how to lower it.
Your birth certificate measures one thing: how many times the Earth has gone round the sun since you were born. It says nothing about how well your cardiovascular system, immune function or metabolism are actually holding up. PhenoAge does.
What is PhenoAge?
PhenoAge is a biological-age metric published by Dr Morgan Levine in 2018. It combines nine standard blood markers with your chronological age to estimate your phenotypic age — a number that, in the original cohort, predicted 10-year mortality more accurately than chronological age alone.
The nine markers
Albumin, creatinine, fasting glucose, C-reactive protein, lymphocyte percentage, mean corpuscular volume (MCV), red cell distribution width (RDW), alkaline phosphatase and white blood cell count. All nine appear on a standard CMP + CBC panel that costs very little.
Can you lower it?
Yes. Six of the nine markers are highly modifiable through diet, training, sleep and inflammation control — CRP and fasting glucose respond especially fast. Most people see measurable change within 8–12 weeks of consistent intervention.
Two 50-year-olds can have PhenoAges of 42 and 58 — and 10-year mortality risk that differs by an order of magnitude.
Calculate yours free with our PhenoAge calculator, then let Misi track it over time and rewrite your plan to drive it down.
Ready to put this into practice?
Misi BioLabs turns your bloods into a meal plan, training block and AI coaching — in one place.
Start freeFree tools
- PhenoAge Calculator — Biological age from a standard blood panel (Levine 2018).
- VO2max Calculator — Cooper 12-minute test → VO2max + fitness age + mortality hazard.
- TDEE & Macro Calculator — Mifflin-St Jeor maintenance calories + protein/fat targets.